Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538020 | 1.00 | KDM4E (0.37) | KDM4EMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL9536949 | 0.88 | LMNA (0.36) | KDM4EMEN1KMT2AALDH1A1ALDH2 | |
| SCHEMBL9536946 | 0.88 | LMNA (0.36) | KDM4EMEN1KMT2AALDH1A1ALDH2 | |
| SCHEMBL8230676 | 0.86 | KCNA3 (0.48) | MEN1KMT2AKCNA3 | |
| SCHEMBL9540647 | 0.83 | LMNA (0.39) | KDM4EMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL9540652 | 0.83 | LMNA (0.39) | KDM4EMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL9539218 | 0.76 | ADORA3 (0.41) | KDM4EMEN1KMT2AALDH1A1ALDH2 | |
| SCHEMBL9539213 | 0.76 | ADORA3 (0.41) | KDM4EMEN1KMT2AALDH1A1ALDH2 | |
| SCHEMBL9539134 | 0.75 | CNR1 (0.37) | KDM4EMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL9539130 | 0.75 | CNR1 (0.37) | KDM4EMEN1KMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0180352-B1 | BENZENE-FUSED HETEROCYCLIC COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-26 | — | — | EP | disclosed |
| US-4767780-A | SUBSTITUTED 1,4-DIHYDRO-(1)-BENZOPYRANO(4,3-C)PYRAZOLES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-08-30 | — | — | US | disclosed |
| US-4675324-A | Substituted pyrazolo [4,3-c]pyridines and their use as uricosuric, diuretic and anti-hypertensive agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-06-23 | — | — | US | disclosed |