Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 16/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7669465 | 0.83 | ADRB3 (0.44) | TACR3TACR1KDM4EKMT2AL3MBTL1 | |
| SCHEMBL9338635 | 0.75 | TACR1 (0.55) | TACR3TACR1 | |
| SCHEMBL9540664 | 0.75 | TACR1 (0.55) | TACR3TACR1 | |
| SCHEMBL9540669 | 0.75 | TACR1 (0.55) | TACR3TACR1 | |
| SCHEMBL9538034 | 0.74 | TACR3 (0.54) | TACR3TACR1 | |
| SCHEMBL9538103 | 0.74 | TACR1 (0.38) | TACR3TACR1 | |
| SCHEMBL8715712 | 0.74 | TACR3 (0.50) | TACR3TACR1 | |
| SCHEMBL9539175 | 0.74 | ADRB3 (0.44) | TACR3TACR1KMT2A | |
| SCHEMBL9519964 | 0.73 | TACR1 (0.48) | TACR3TACR1 | |
| SCHEMBL8892928 | 0.69 | TACR1 (0.57) | TACR3TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003721-A1 | CHOLECYSTOKININ ANTAGONISTS USEFUL FOR TREATING DEPRESSION | WARNER-LAMBERT COMPANY (US) | 1993-03-04 | — | — | WO | disclosed |