Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 9/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | MMP9 | P14780 | 3/20 | 0.38 |
| ▸ | MMP8 | P22894 | 3/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6888854 | 0.75 | TACR1 (0.46) | TACR1TACR3ADRB3 | |
| SCHEMBL9539175 | 0.75 | ADRB3 (0.44) | TACR1TACR3ADRB3MMP9MMP8 | |
| SCHEMBL9538112 | 0.74 | TACR3 (0.45) | TACR1TACR3 | |
| SCHEMBL8705433 | 0.72 | TACR1 (0.46) | TACR1TACR3ADRB3 | |
| SCHEMBL8715705 | 0.70 | TACR1 (0.46) | TACR1TACR3ADRB3 | |
| SCHEMBL9541550 | 0.69 | TACR1 (0.43) | TACR1TACR3 | |
| SCHEMBL9293660 | 0.68 | TACR1 (0.48) | TACR1TACR3 | |
| SCHEMBL8892928 | 0.67 | TACR1 (0.57) | TACR1TACR3 | |
| SCHEMBL7669465 | 0.67 | ADRB3 (0.44) | TACR1TACR3ADRB3 | |
| SCHEMBL8485370 | 0.67 | TACR1 (0.61) | TACR1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003721-A1 | CHOLECYSTOKININ ANTAGONISTS USEFUL FOR TREATING DEPRESSION | WARNER-LAMBERT COMPANY (US) | 1993-03-04 | — | — | WO | disclosed |