Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536434 | 0.88 | TOP2A (0.49) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15920967 | 0.85 | KDM4E (0.77) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL17280352 | 0.82 | KDM4E (0.69) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4096679 | 0.81 | KDM4E (0.85) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10404849 | 0.79 | KDM4E (0.57) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15932525 | 0.75 | KDM4E (0.65) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15920662 | 0.74 | MAPT (0.72) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| Cilinaphthalide B SCHEMBL15920690 | 0.74 | MAPT (0.63) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15920749 | 0.74 | ALDH1A1 (0.71) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15920805 | 0.74 | KDM4E (0.71) | KDM4EALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386778-B1 | BIPHENYL DERIVATIVES | TANABE SEIYAKU CO., LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |
| US-5169861-A | Therapeutic or prophylactic agent for hepatic diseases | TANABE SEIYAKU CO., LTD. (JP) | 1992-12-08 | — | — | US | disclosed |
| US-5066669-A | Hepatitis, liver disorders | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-19 | — | — | US | disclosed |
| EP-0386778-A1 | Biphenyl derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |