Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | AGER | Q15109 | 1/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10538765 | 0.82 | LMNA (0.51) | LMNATSHRKMT2AMEN1KDM4E | |
| SCHEMBL4089127 | 0.81 | LMNA (0.48) | LMNATSHRKMT2AMEN1KDM4E | |
| SCHEMBL2854775 | 0.78 | HSD17B10 (0.57) | LMNATSHRKMT2AKDM4EMAPK1 | |
| SCHEMBL6910150 | 0.78 | TSHR (0.53) | LMNATSHRKMT2AMEN1KDM4E | |
| SCHEMBL28923753 | 0.78 | APAF1 (0.56) | LMNATSHRKMT2AMEN1KDM4E | |
| SCHEMBL6282436 | 0.78 | TSHR (0.53) | LMNATSHRKMT2AMEN1KDM4E | |
| SCHEMBL13870967 | 0.77 | SLC6A2 (0.57) | — | |
| SCHEMBL4077337 | 0.77 | SLC6A2 (0.57) | — | |
| Hydrochloric Acid SCHEMBL4079007 | 0.76 | SLC6A2 (0.57) | — | |
| SCHEMBL18250744 | 0.74 | HTT (0.55) | LMNATSHRKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527817-A1 | GAMMA-BUTYROLACTOL ETHER DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-02-24 | — | — | EP | disclosed |
| WO-1991017157-A1 | GAMMA-BUTYROLACTOL ETHER DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1991-11-14 | — | — | WO | disclosed |