SCHEMBL9538309

SCHEMBL9538309

O=C[SiH2]O[SiH2]c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
CYP2A6 P11509 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3679065 0.77 TSHR (0.37) ALDH1A1
SCHEMBL27508472 0.72
SCHEMBL28439029 0.71 ALDH1A1 (0.36) ALDH1A1CYP2A6
SCHEMBL11881468 0.69 TSHR (0.30)
SCHEMBL28864191 0.67
SCHEMBL2153932 0.65
SCHEMBL27508473 0.64 MAPT (0.32)
SCHEMBL27779012 0.64 TDP1 (0.30)
SCHEMBL17763370 0.64
SCHEMBL29262755 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0182503-B1 OPHTHALMIC GLASS/PLASTIC LAMINATED LENS HAVING PHOTOCHROMIC CHARACTERISTICS Ace, Ronald Stephen (US) 1993-09-08 EP disclosed
US-4679918-A LIGHTWEIGHT ACE RONALD S (US) 1987-07-14 US disclosed
EP-0182503-A2 Ophthalmic glass/plastic laminated lens having photochromic characteristics Ace, Ronald Stephen (US) 1986-05-28 EP disclosed
WO-1986002742-A1 OPHTHALMIC GLASS/PLASTIC LAMINATED LENS HAVING PHOTOCHROMIC CHARACTERISTICS AND METHOD OF ASSEMBLY THEREOF ACE RONALD S 1986-05-09 WO disclosed