Ether

Ether

SCHEMBL9538327

CCOCC.c1ccc(COCc2ccccc2-c2ccccc2)cc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 1/20 0.56
TSHR P16473 1/20 0.50
DPP4 P27487 1/20 0.43
FFAR1 O14842 4/20 0.42
FFAR4 Q5NUL3 4/20 0.42
CHRNB2 P17787 2/20 0.42
CHRNA4 P43681 2/20 0.42
CHRNB4 P30926 1/20 0.40
CHRNA3 P32297 1/20 0.40
PTGER1 P34995 3/20 0.39
PTGER4 P35408 3/20 0.39
PTGER3 P43115 3/20 0.39
PTGER2 P43116 3/20 0.39
PPARA Q07869 2/20 0.39
PPARG P37231 1/20 0.39
CD274 Q9NZQ7 2/20 0.39
PDCD1 Q15116 1/20 0.39
KMT2A Q03164 1/20 0.38
KDM4E B2RXH2 1/20 0.37
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10599800 0.91 TACR1 (0.64) TACR1TSHRDPP4FFAR1FFAR4
SCHEMBL16390993 0.91 TACR1 (0.64) TACR1TSHRDPP4FFAR1FFAR4
Water SCHEMBL9538330 0.90 TACR1 (0.62) TACR1TSHRDPP4FFAR1FFAR4
SCHEMBL8679174 0.88 TACR1 (0.51) TACR1DPP4FFAR1FFAR4CHRNB2
SCHEMBL1338113 0.86 TACR1 (0.48) TACR1TSHRDPP4FFAR1FFAR4
SCHEMBL336977 0.84 TACR1 (0.62) TACR1TSHRDPP4FFAR1FFAR4
SCHEMBL12330434 0.83 TACR1 (0.56) TACR1TSHRDPP4FFAR1FFAR4
Ether SCHEMBL10609432 0.82 TSHR (0.75) TACR1TSHRKDM4EPOLB
Ether SCHEMBL19744986 0.82 TSHR (0.75) TACR1TSHRKDM4EPOLB
Ether SCHEMBL9719794 0.80 DPP4 (0.50) TACR1DPP4FFAR1FFAR4PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5032054-A None JP disclosed
JP-H0532054-A THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LTD 1993-02-09 JP disclosed