SCHEMBL8679174

SCHEMBL8679174

CCOCc1ccccc1-c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 1/20 0.51
DPP4 P27487 1/20 0.50
CHRNB2 P17787 2/20 0.47
CHRNA4 P43681 2/20 0.47
PDCD1 Q15116 1/20 0.44
CD274 Q9NZQ7 1/20 0.44
FFAR1 O14842 5/20 0.43
FFAR4 Q5NUL3 4/20 0.43
KMT2A Q03164 1/20 0.43
CARM1 Q86X55 1/20 0.40
PRMT6 Q96LA8 1/20 0.40
GBA1 P04062 2/20 0.39
LCT P09848 2/20 0.39
SI P14410 2/20 0.39
UGCG Q16739 2/20 0.39
GBA2 Q9HCG7 2/20 0.39
MGAM O43451 1/20 0.39
CHRNB4 P30926 1/20 0.39
CHRNA3 P32297 1/20 0.39
FABP7 O15540 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL9538327 0.88 TACR1 (0.56) TACR1DPP4CHRNB2CHRNA4PDCD1
SCHEMBL336977 0.87 TACR1 (0.62) TACR1DPP4CHRNB2CHRNA4PDCD1
SCHEMBL21796063 0.87 TACR1 (0.38) TACR1DPP4CHRNB2CHRNA4FFAR1
SCHEMBL1338113 0.87 TACR1 (0.48) TACR1DPP4CHRNB2CHRNA4FFAR1
SCHEMBL8125619 0.85 FFAR1 (0.46) TACR1DPP4CHRNB2CHRNA4FFAR1
SCHEMBL3465996 0.85 FFAR1 (0.46) TACR1DPP4CHRNB2CHRNA4FFAR1
SCHEMBL2345310 0.85 CD274 (0.43) TACR1DPP4CHRNB2CHRNA4PDCD1
SCHEMBL27914973 0.85 TACR1 (0.49) TACR1DPP4CHRNB2CHRNA4PDCD1
Ether SCHEMBL9719794 0.84 DPP4 (0.50) TACR1DPP4PDCD1CD274FFAR1
SCHEMBL9338655 0.83 TACR1 (0.58) TACR1DPP4CHRNB2CHRNA4PDCD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110003616-B Epoxy resin composition and cured product thereof 日铁化学材料株式会社 2024-01-09 CN disclosed
CN-116348522-A Alkali-soluble resin containing polymerizable unsaturated group, photosensitive resin composition containing the resin as essential component, and cured product thereof 日铁化学材料株式会社 2023-06-27 CN disclosed
CN-115836101-A Curable resin, curable resin composition, and cured product DIC株式会社 2023-03-21 CN disclosed
CN-114989376-A Phenolic resin, epoxy resin and condensate thereof 上海衡封新材料科技有限公司 2022-09-02 CN disclosed
CN-110922717-A Epoxy resin composition, prepreg, laminate, and printed wiring board 日铁化学材料株式会社 2020-03-27 CN disclosed
US-20120232062-A1 AZAINDAZOLES TO TREAT FLAVIVIRIDAE VIRUS INFECTION EIGER BIOPHARMACEUTICALS, INC. (US) 2012-09-13 US disclosed
US-7687459-B2 Arylalkoxyl hepatitis C virus protease inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2010-03-30 US disclosed
US-20090041721-A1 serine protease inhibitors; interferons ENANTA PHARMACEUTICALS, INC. 2009-02-12 US disclosed
US-7226950-B2 Sodium channel modulators THERAVANCE, INC. (US) 2007-06-05 US disclosed
US-5780571-A RESIN OBTAINED BY CONDENSATION OF NAPHTHOL AND 4,4*-BIS/CHLOROMETHYL/BIPHENYL, OPTIONALLY REACTED WITH EPICHLOROHYDRIN NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1998-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120232062-A1 AZAINDAZOLES TO TREAT FLAVIVIRIDAE VIRUS INFECTION HAVCR2, AZI2, ZC3HAV1 TACR1 3695/4885DPP4 343/4885CHRNB2 4761/4885
US-20090041721-A1 serine protease inhibitors; interferons PRSS1, SERPINB1, SPINT2 TACR1 1182/4885DPP4 16/4885CHRNB2 4877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.