Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 8/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | HRH2 | P25021 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9538448 | 1.00 | HRH1 (0.44) | HRH1SLC6A9MAPTOPRM1OPRD1 | |
| Oxalic Acid SCHEMBL9539822 | 0.96 | HRH1 (0.47) | HRH1SLC6A9MAPTOPRM1OPRD1 | |
| Oxalic Acid SCHEMBL9539814 | 0.96 | HRH1 (0.47) | HRH1SLC6A9MAPTOPRM1OPRD1 | |
| Oxalic Acid SCHEMBL10383155 | 0.88 | SLC6A9 (0.41) | HRH1SLC6A9MAPTOPRM1OPRD1 | |
| SCHEMBL9535303 | 0.88 | SLC6A9 (0.44) | HRH1SLC6A9MAPTOPRM1OPRD1 | |
| Oxalic Acid SCHEMBL9535612 | 0.87 | HRH1 (0.46) | HRH1SLC6A9MAPTOPRM1OPRD1 | |
| Oxalic Acid SCHEMBL9536954 | 0.87 | SLC6A9 (0.41) | HRH1SLC6A9MAPTOPRM1OPRD1 | |
| Oxalic Acid SCHEMBL9536963 | 0.87 | SLC6A9 (0.41) | HRH1SLC6A9MAPTOPRM1OPRD1 | |
| Oxalic Acid SCHEMBL9535618 | 0.87 | HRH1 (0.46) | HRH1SLC6A9MAPTOPRM1OPRD1 | |
| SCHEMBL9535360 | 0.87 | HRH1 (0.54) | HRH1SLC6A9MAPTOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282133-B1 | 1-ALKYL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-28 | — | — | EP | disclosed |
| US-4943580-A | ANTIALLERGENS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-07-24 | — | — | US | disclosed |