Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 9/20 | 0.54 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | EED | O75530 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HLA-A | P04439 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9539814 | 0.91 | HRH1 (0.47) | HRH1SLC6A9KCNH2MAPTOPRM1 | |
| Oxalic Acid SCHEMBL9539822 | 0.91 | HRH1 (0.47) | HRH1SLC6A9KCNH2MAPTOPRM1 | |
| SCHEMBL9536097 | 0.90 | SLC6A9 (0.45) | HRH1SLC6A9KCNH2MAPTOPRM1 | |
| SCHEMBL9535868 | 0.89 | SLC6A9 (0.44) | HRH1SLC6A9KCNH2MAPTCHRM1 | |
| Hydrochloric Acid SCHEMBL10384124 | 0.88 | SLC6A9 (0.44) | HRH1SLC6A9KCNH2MAPTCHRM1 | |
| SCHEMBL9535303 | 0.88 | SLC6A9 (0.44) | HRH1SLC6A9KCNH2MAPTOPRM1 | |
| SCHEMBL10382570 | 0.88 | SLC6A9 (0.44) | HRH1SLC6A9KCNH2MAPTOPRM1 | |
| SCHEMBL10383142 | 0.87 | SLC6A9 (0.45) | HRH1SLC6A9KCNH2MAPTOPRM1 | |
| SCHEMBL9537031 | 0.87 | SLC6A9 (0.42) | HRH1SLC6A9KCNH2MAPTSSTR5 | |
| SCHEMBL9536586 | 0.87 | SLC6A9 (0.41) | HRH1SLC6A9KCNH2MAPTOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282133-B1 | 1-ALKYL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-28 | — | — | EP | disclosed |
| US-4943580-A | ANTIALLERGENS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-07-24 | — | — | US | disclosed |
| EP-0282133-A2 | 1-alkyl substituted benzimidazole derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-09-14 | — | — | EP | disclosed |