Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CPT2 | P23786 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6898351 | 0.79 | KDM4E (0.48) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL2973761 | 0.77 | — | — | |
| Meglutol SCHEMBL28443 | 0.77 | HMGCR (1.00) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| Meglutol SCHEMBL8718194 | 0.77 | HMGCR (1.00) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL2708250 | 0.77 | TSHR (0.36) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL2708246 | 0.77 | TSHR (0.36) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL2010919 | 0.76 | HMGCR (0.41) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL10781696 | 0.74 | KMT2A (0.44) | HMGCRCHRM1TBXA2RADRA1ATSHR | |
| SCHEMBL29233028 | 0.73 | ALDH1A1 (0.37) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| Acetic Acid SCHEMBL8752671 | 0.71 | FFAR3 (0.35) | HMGCRCHRM1TBXA2RADRA1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178106-B1 | ENZYMATIC PROCESS | NOVO NORDISK A/S (DK) | 1993-03-31 | — | — | EP | disclosed |
| CN-85107055-A | EMZYMATIC PROCESS | — | 1986-06-10 | — | — | CN | disclosed |
| EP-0178106-A2 | Enzymatic process | NOVO NORDISK A/S (DK) | 1986-04-16 | — | — | EP | disclosed |