SCHEMBL9538536

SCHEMBL9538536

COC1CN(C)Sc2sccc21

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11727643 0.54 HRH1 (0.39)
SCHEMBL5728818 0.53 HRH1 (0.35)
SCHEMBL9682581 0.50 HTT (0.35)
SCHEMBL16548490 0.48
SCHEMBL926504 0.47
SCHEMBL18959593 0.47 IDO1 (0.44)
SCHEMBL26427796 0.47
SCHEMBL3592638 0.46
Ethylene SCHEMBL27784020 0.46 GPR35 (0.37)
SCHEMBL9035702 0.45

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0527801-A4 THIOPHENE SULFONAMIDES USEFUL AS CARBONIC ANYDRASE INHIBITORS 1993-03-10 EP disclosed
EP-0527801-A1 THIOPHENE SULFONAMIDES USEFUL AS CARBONIC ANYDRASE INHIBITORS ALCON LABORATORIES, INC. (US) 1993-02-24 EP disclosed
WO-1991015486-A1 THIOPHENE SULFONAMIDES USEFUL AS CARBONIC ANYDRASE INHIBITORS ALCON LABORATORIES, INC. (US) 1991-10-17 WO disclosed