Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538543 | 1.00 | KDM4E (0.46) | KDM4EKMT2AGAAPOLBLMNA | |
| SCHEMBL9541099 | 0.84 | STING1 (0.49) | KDM4EALDH1A1SMN1; SMN2STING1HSD17B10 | |
| SCHEMBL9541095 | 0.84 | STING1 (0.49) | KDM4EALDH1A1SMN1; SMN2STING1HSD17B10 | |
| SCHEMBL9539437 | 0.79 | CYP2A6 (0.47) | KDM4EPOLBLMNAALDH1A1STING1 | |
| SCHEMBL9540314 | 0.76 | FDPS (0.50) | STING1CYP3A4ESR1 | |
| SCHEMBL9540978 | 0.75 | MAPK1 (0.43) | KMT2AGAAPOLBLMNAALDH1A1 | |
| SCHEMBL9540983 | 0.75 | MAPK1 (0.43) | KMT2AGAAPOLBLMNAALDH1A1 | |
| Tibenelast SCHEMBL449748 | 0.75 | STING1 (0.54) | ALDH1A1STING1TSHRHSD17B10 | |
| Tibenelast SCHEMBL10688452 | 0.74 | STING1 (0.53) | ALDH1A1STING1TSHRHSD17B10 | |
| SCHEMBL8378668 | 0.74 | STING1 (0.44) | GLASTING1TSHRHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993005033-A1 | BENZO[b]THIOPHENE DERIVATES, PROCESS FOR PRODUCING THE SAME AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1993-03-18 | — | — | WO | disclosed |