Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | STING1 | Q86WV6 | 9/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541095 | 0.82 | STING1 (0.49) | STING1 | |
| SCHEMBL9541099 | 0.82 | STING1 (0.49) | STING1 | |
| SCHEMBL6965215 | 0.78 | CYP2A6 (0.47) | FDPSMAOBDPP4ALOX5CYP3A4 | |
| SCHEMBL6965217 | 0.78 | CYP2A6 (0.47) | FDPSMAOBDPP4ALOX5CYP3A4 | |
| SCHEMBL29709927 | 0.78 | TTR (0.43) | FDPSMAOBESR1DPP4CYP3A4 | |
| SCHEMBL6965431 | 0.78 | MAPT (0.44) | FDPSMAOBESR1DPP4CYP3A4 | |
| SCHEMBL6965434 | 0.78 | MAPT (0.44) | FDPSMAOBESR1DPP4CYP3A4 | |
| SCHEMBL6964345 | 0.78 | IDO1 (0.43) | FDPSMAOBESR1DPP4CYP3A4 | |
| SCHEMBL6964344 | 0.78 | IDO1 (0.43) | FDPSMAOBESR1DPP4CYP3A4 | |
| SCHEMBL13790852 | 0.77 | FDPS (0.40) | FDPSMAOBESR1DPP4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993005033-A1 | BENZO[b]THIOPHENE DERIVATES, PROCESS FOR PRODUCING THE SAME AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1993-03-18 | — | — | WO | disclosed |