Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534385 | 0.85 | TAS2R14 (0.44) | TAS2R14KDM4ELMNATP53ALDH1A1 | |
| SCHEMBL9039484 | 0.85 | TAS2R14 (0.46) | TAS2R14GRM1KDM4ELMNAALDH1A1 | |
| SCHEMBL9039344 | 0.83 | HTT (0.46) | TAS2R14GRM1KDM4ERAB9ALMNA | |
| SCHEMBL9039454 | 0.83 | TAS2R14 (0.46) | TAS2R14GRM1KDM4ELMNATP53 | |
| SCHEMBL9038372 | 0.83 | TAS2R14 (0.46) | TAS2R14KDM4ELMNATP53ALDH1A1 | |
| SCHEMBL9039797 | 0.82 | TAS2R14 (0.48) | TAS2R14KDM4ELMNATP53ALDH1A1 | |
| SCHEMBL9039947 | 0.79 | TAS2R14 (0.44) | TAS2R14KDM4ELMNATP53ALDH1A1 | |
| SCHEMBL9037923 | 0.79 | TAS2R14 (0.46) | TAS2R14KDM4ELMNATP53ALDH1A1 | |
| SCHEMBL9038676 | 0.78 | TAS2R14 (0.48) | TAS2R14KDM4ELMNATP53ALDH1A1 | |
| SCHEMBL10757636 | 0.78 | TAS2R14 (0.39) | TAS2R14KDM4ELMNATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243311-A2 | Pyrido[2,3-d]pyrimidine derivatives | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1987-10-28 | — | — | EP | claimed |
| EP-0243311-B1 | Pyrido[2,3-d]pyrimidine derivatives | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |
| US-4808587-A | ANTIALLEGENS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1989-02-28 | — | — | US | disclosed |
| EP-0243311-A2 | Pyrido[2,3-d]pyrimidine derivatives | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1987-10-28 | — | — | EP | disclosed |