Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.46 |
| ▸ | PCSK9 | Q8NBP7 | 8/20 | 0.45 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538645 | 0.85 | TAS2R14 (0.46) | TAS2R14GRM1LMNAKDM4EALDH1A1 | |
| SCHEMBL9039797 | 0.81 | TAS2R14 (0.48) | TAS2R14LMNAKDM4EADORA2BALDH1A1 | |
| SCHEMBL9534385 | 0.81 | TAS2R14 (0.44) | TAS2R14LMNAMEN1KMT2AKDM4E | |
| SCHEMBL9039344 | 0.80 | HTT (0.46) | TAS2R14GRM1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL9038372 | 0.80 | TAS2R14 (0.46) | TAS2R14LMNAKDM4EADORA2BALDH1A1 | |
| SCHEMBL9039454 | 0.80 | TAS2R14 (0.46) | TAS2R14GRM1LMNAKDM4EADORA2B | |
| SCHEMBL9038676 | 0.78 | TAS2R14 (0.48) | TAS2R14LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9039947 | 0.76 | TAS2R14 (0.44) | TAS2R14LMNAKDM4EADORA2BALDH1A1 | |
| SCHEMBL9037923 | 0.76 | TAS2R14 (0.46) | TAS2R14LMNAMEN1KMT2AKDM4E | |
| SCHEMBL9537419 | 0.76 | UTS2R (0.44) | PCSK9LMNAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243311-A2 | Pyrido[2,3-d]pyrimidine derivatives | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1987-10-28 | — | — | EP | claimed |
| EP-0696590-A1 | Pyrido[2,3-d]pyrimidine derivatives, their preparation and their use as anti-asthma agents | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |
| EP-0243311-B1 | Pyrido[2,3-d]pyrimidine derivatives | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |
| US-4808587-A | ANTIALLEGENS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1989-02-28 | — | — | US | disclosed |
| EP-0243311-A2 | Pyrido[2,3-d]pyrimidine derivatives | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1987-10-28 | — | — | EP | disclosed |