SCHEMBL953871

SCHEMBL953871

O=C(CCl)c1ccc(Cl)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 3/20 1.00
ALDH1A1 P00352 6/20 0.62
HIF1A Q16665 3/20 0.62
MAPK1 P28482 2/20 0.62
TRPA1 O75762 1/20 0.62
ERCC5 P28715 1/20 0.57
FEN1 P39748 1/20 0.57
CES2 O00748 1/20 0.56
CES1 P23141 1/20 0.56
MAPT P10636 4/20 0.55
L3MBTL1 Q9Y468 3/20 0.55
ALOX15 P16050 1/20 0.54
TSHR P16473 1/20 0.54
RAB9A P51151 3/20 0.53
NPC1 O15118 2/20 0.53
TP53 P04637 1/20 0.53
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
KDM4E B2RXH2 1/20 0.52
LMNA P02545 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL27987336 0.95 GSK3B (0.91) GSK3BALDH1A1HIF1AMAPK1TRPA1
Formaldehyde SCHEMBL28234403 0.95 GSK3B (0.91) GSK3BALDH1A1HIF1AMAPK1TRPA1
SCHEMBL28874706 0.93 GSK3B (0.87) GSK3BALDH1A1HIF1AMAPK1TRPA1
SCHEMBL25224307 0.93 GSK3B (0.87) GSK3BALDH1A1HIF1AMAPK1TRPA1
SCHEMBL28574433 0.89 GSK3B (0.80) GSK3BALDH1A1HIF1AMAPK1TRPA1
SCHEMBL11480265 0.89 GSK3B (0.80) GSK3BALDH1A1HIF1AMAPK1TRPA1
SCHEMBL15756687 0.88 GSK3B (0.77) GSK3BALDH1A1HIF1AMAPK1TRPA1
SCHEMBL11002539 0.83 ALDH1A1 (0.83) GSK3BALDH1A1HIF1AMAPK1TRPA1
SCHEMBL10886301 0.82 GSK3B (0.70) GSK3BALDH1A1HIF1AMAPK1TRPA1
SCHEMBL16552727 0.82 GSK3B (0.70) GSK3BALDH1A1ERCC5FEN1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 802 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119614529-A Short-chain dehydrogenase, engineering bacteria and application thereof in asymmetric reduction of potential chiral carbonyl compounds 杭州文德阶生物科技有限公司 2025-03-14 CN claimed
CN-117210193-A Ultraviolet-resistant UV adhesive and preparation method thereof 广东阿普邦新材料科技股份有限公司 2023-12-12 CN claimed
CN-116041309-B Continuous extraction synthesis method of substituted ketal 浙江宇龙生物科技股份有限公司 2023-11-14 CN claimed
CN-219168425-U Production equipment of 2, 4-dichloro acetophenone 江苏隆昌化工有限公司 2023-06-13 CN claimed
CN-116041309-A Continuous extraction synthesis method of substituted ketal 浙江宇龙生物科技股份有限公司 2023-05-02 CN claimed
CN-111253233-B Transposition method of acetophenone isomer 浙江禾本科技股份有限公司 2023-02-28 CN claimed
CN-112522224-B Alcohol dehydrogenase mutant with improved activity and stereoselectivity, recombinant vector, genetic engineering bacteria and application thereof 华东理工大学 2022-12-23 CN claimed
CN-113231089-B Preparation method and application of supported phosphotungstic acid or phosphotungstate solid acid catalyst 南京工业大学 2022-08-30 CN claimed
CN-109400541-B Process for the preparation of cyproconazole from 1-chloro-2- (4-chlorophenyl) -3-methyl-4-penten-2-ol 淮安国瑞化工有限公司 2022-05-17 CN claimed
CN-109400542-B Preparation method of cyproconazole 淮安国瑞化工有限公司 2022-05-13 CN claimed
US-20110288315-A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE COMPOUND DAISO CO., LTD. (JP) 2011-11-24 US claimed
CN-101781290-B New method for producing propiconazole LIMIN CHEMICAL CO LTD 2011-11-09 CN claimed
CN-102225935-A Manufacturing method of proPiconazole SHANDONG WEIFANG SHUANGXING PESTICIDE CO LTD 2011-10-26 CN claimed
EP-2377376-A1 METHOD TO FORM SOLDER DEPOSITS ON SUBSTRATES ATOTECH Deutschland GmbH (DE) 2011-10-19 EP claimed
US-20110189848-A1 METHOD TO FORM SOLDER DEPOSITS ON SUBSTRATES ATOTECH DEUTSCHLAND GMBH & CO. KG (F/K/A ATOTECH DEUTSCHLAND GMBH) (DE) 2011-08-04 US claimed
EP-2325178-A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE COMPOUND DAISO CO., LTD. (JP) 2011-05-25 EP claimed
CN-101781290-A New method for producing propiconazole LIMIN CHEMICAL CO LTD 2010-07-21 CN claimed
WO-2010046235-A1 METHOD TO FORM SOLDER DEPOSITS ON SUBSTRATES ATOTECH DEUTSCHLAND GMBH (DE) 2010-04-29 WO claimed
CN-101323612-A Preparation of bactericide propiconazole JIANGSU SEVENCONTINENT GREEN C (CN) 2008-12-17 CN claimed
US-4417957-A CHLORINATED ACETOPHENONES; ACRYLIC ACID AND/OR METHACRYLIC ACID COLUMBIA CHEMICAL CORPORATION (US) 1983-11-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110288315-A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE COMPOUND CYP51A1, KMO, TALDO1 GSK3B 776/4885ALDH1A1 453/4885HIF1A 1833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.