Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 16/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538200 | 0.87 | APP (0.68) | APPCYP1A2MEN1ALDH1A1POLB | |
| SCHEMBL5085776 | 0.83 | APP (0.61) | APPCYP1A2KDM4EMEN1ALDH1A1 | |
| SCHEMBL9749591 | 0.81 | APP (0.59) | APPCYP1A2 | |
| SCHEMBL1635563 | 0.80 | APP (0.68) | APPCYP1A2KDM4EMEN1ALDH1A1 | |
| SCHEMBL8066 | 0.80 | APP (1.00) | APPCYP1A2MEN1POLBKMT2A | |
| Ammonia Solution, Strong SCHEMBL29419058 | 0.78 | APP (0.97) | APPCYP1A2MEN1POLBKMT2A | |
| SCHEMBL1095367 | 0.78 | APP (0.97) | APPCYP1A2MEN1POLBKMT2A | |
| SCHEMBL7113427 | 0.78 | APP (0.97) | APPCYP1A2MEN1POLBKMT2A | |
| SCHEMBL29456578 | 0.78 | APP (0.97) | APPCYP1A2MEN1POLBKMT2A | |
| Pyridine SCHEMBL8601041 | 0.77 | APP (0.54) | APPCYP1A2MEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242805-A | Useful in directingcells producing enzymes that hydrolyze the glycoside | MOLECULAR PROBES, INC. (US) | 1993-09-07 | — | — | US | disclosed |
| WO-1993004074-A1 | LONG WAVELENGTH LIPOPHILIC FLUOROGENIC GLYCOSIDASE SUBSTRATES | MOLECULAR PROBES, INC. (US) | 1993-03-04 | — | — | WO | disclosed |