Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.65 |
| ▸ | HRH1 | P35367 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416758 | 0.85 | KCNH2 (0.65) | KCNH2TSHRACHE | |
| SCHEMBL9698375 | 0.82 | KCNH2 (0.66) | KCNH2TSHRCHRNA7 | |
| Water SCHEMBL8566156 | 0.81 | KCNH2 (0.61) | KCNH2 | |
| SCHEMBL8560605 | 0.81 | KCNH2 (0.61) | KCNH2 | |
| Water SCHEMBL8562628 | 0.81 | KCNH2 (0.61) | KCNH2 | |
| SCHEMBL11266594 | 0.81 | KCNH2 (0.80) | KCNH2TSHRCHRNA7 | |
| Hydrochloric Acid SCHEMBL8564807 | 0.80 | KCNH2 (0.60) | KCNH2 | |
| SCHEMBL9538063 | 0.79 | KCNH2 (1.00) | KCNH2HRH1 | |
| SCHEMBL9697190 | 0.78 | KCNH2 (0.66) | KCNH2TSHR | |
| SCHEMBL3748349 | 0.78 | KCNH2 (0.63) | KCNH2ACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282133-B1 | 1-ALKYL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-28 | — | — | EP | disclosed |
| US-4943580-A | ANTIALLERGENS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-07-24 | — | — | US | disclosed |
| EP-0282133-A2 | 1-alkyl substituted benzimidazole derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-09-14 | — | — | EP | disclosed |