Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL4774389 | 0.79 | FFAR3 (0.37) | GRIA1GRIA3GRIA2GRIA4GAA | |
| SCHEMBL4437207 | 0.75 | NPSR1 (0.41) | GRIA1GRIA3GRIA2GRIA4GAA | |
| SCHEMBL21940617 | 0.73 | — | — | |
| (R,S)-Ampa SCHEMBL2458874 | 0.71 | GRIA1 (0.69) | GRIA1GRIA3GRIA2GRIA4MEN1 | |
| (S)-Ampa SCHEMBL667915 | 0.71 | GRIA1 (0.69) | GRIA1GRIA3GRIA2GRIA4MEN1 | |
| SCHEMBL9014849 | 0.71 | TLR8 (0.34) | GRIA1GRIA3GAA | |
| (R,S)-Ampa SCHEMBL7200262 | 0.70 | GRIA1 (0.68) | GRIA1GRIA3GRIA2GRIA4MEN1 | |
| (R,S)-Ampa SCHEMBL7200264 | 0.70 | GRIA1 (0.68) | GRIA1GRIA3GRIA2GRIA4MEN1 | |
| SCHEMBL9538911 | 0.70 | GRIA1 (0.40) | GRIA1GRIA3GRIA2GRIA4GAA | |
| SCHEMBL3731488 | 0.69 | GRIA1 (0.54) | GRIA1GRIA3GRIA2GRIA4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993005772-A1 | φ-[2-(PHOSPHONOALKYL)PHENYL]-2-AMINOALKANOIC ACIDS AS ANTAGONISTS OF EXCITATORY AMINO ACID RECEPTORS | NOVA PHARMACEUTICAL CORPORATION (US) | 1993-04-01 | — | — | WO | disclosed |