Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14759391 | 0.79 | LMNA (0.42) | TLR8GAA | |
| SCHEMBL9147234 | 0.79 | GAA (0.32) | GRIA1GRIA3GAA | |
| SCHEMBL21940617 | 0.74 | — | — | |
| SCHEMBL4437207 | 0.73 | NPSR1 (0.41) | GRIA1GRIA3GAA | |
| SCHEMBL3731488 | 0.71 | GRIA1 (0.54) | GRIA1GRIA3 | |
| Propionic Acid SCHEMBL9538907 | 0.71 | GRIA1 (0.40) | GRIA1GRIA3GAA | |
| (R,S)-Ampa SCHEMBL6553747 | 0.70 | GRIA1 (0.56) | GRIA1GRIA3 | |
| SCHEMBL1580004 | 0.68 | LMNA (0.43) | GAA | |
| (S)-Ampa SCHEMBL667915 | 0.66 | GRIA1 (0.69) | GRIA1GRIA3 | |
| (R,S)-Ampa SCHEMBL2458874 | 0.66 | GRIA1 (0.69) | GRIA1GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019145957-A1 | METHOD OF TREATING INTELLECTUAL DISABILITY, AUTISM AND EPILEPSY ASSOCIATED WITH AN IQSEC2 MUTATION AND FOR IDENTIFYING MEDICAMENTS FOR TREATING THE SAME | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2019-08-01 | — | — | WO | disclosed |
| US-5510367-A | TREATMENT OR PREVENTION OF NEUROTOXIC INJURIES SUCH AS CEREBRAL STROKE, HEMMORHAGIC STROKE, CEREBRAL ISCHEMIA, VASOSPASM, HYPOGLYCEMIA, ANAESIA, HYPOXIA, ASHYXIA, CARDIAC ARREST AND NEURODEGENERATIVE DISEASES | GLAXO SPA (IT) | 1996-04-23 | — | — | US | disclosed |