Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538971 | 1.00 | HPGD (0.43) | HPGDALDH1A1SMN1; SMN2MEN1TSHR | |
| SCHEMBL9538872 | 1.00 | HPGD (0.43) | HPGDALDH1A1SMN1; SMN2MEN1TSHR | |
| SCHEMBL9540499 | 0.92 | HPGD (0.45) | HPGDALDH1A1SMN1; SMN2MEN1TSHR | |
| SCHEMBL9540520 | 0.92 | HPGD (0.45) | HPGDALDH1A1SMN1; SMN2MEN1TSHR | |
| SCHEMBL9540513 | 0.92 | HPGD (0.45) | HPGDALDH1A1SMN1; SMN2MEN1TSHR | |
| SCHEMBL9537005 | 0.87 | MEN1 (0.54) | ALDH1A1SMN1; SMN2MEN1TSHRKMT2A | |
| SCHEMBL9537009 | 0.87 | MEN1 (0.54) | ALDH1A1SMN1; SMN2MEN1TSHRKMT2A | |
| SCHEMBL9537021 | 0.87 | MEN1 (0.54) | ALDH1A1SMN1; SMN2MEN1TSHRKMT2A | |
| SCHEMBL2467775 | 0.82 | KMT2A (0.50) | HPGDALDH1A1SMN1; SMN2MEN1TSHR | |
| SCHEMBL9019840 | 0.78 | HPGD (0.46) | HPGDALDH1A1SMN1; SMN2MEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993006112-A1 | THERAPEUTIC NUCLEOSIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-01 | — | — | WO | disclosed |