SCHEMBL2467775

SCHEMBL2467775

CC(=O)Nc1nc2ncn(COC(COC(C)=O)COC(C)=O)c2c(=O)[nH]1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
TSHR P16473 1/20 0.50
HPGD P15428 1/20 0.43
GDA Q9Y2T3 1/20 0.41
KDM4E B2RXH2 1/20 0.40
GAA P10253 1/20 0.40
ALDH1A1 P00352 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
PDE3A Q14432 1/20 0.38
FGFR1 P11362 1/20 0.36
FGFR2 P21802 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9019840 0.90 HPGD (0.46) KMT2AMEN1TSHRHPGDGDA
SCHEMBL2464875 0.84 PDE3A (0.50) KMT2AMEN1TSHRHPGDKDM4E
SCHEMBL2467673 0.84 MEN1 (0.71) KMT2AMEN1TSHRKDM4EGAA
SCHEMBL8444827 0.83 MEN1 (0.71) KMT2AMEN1TSHRHPGDGDA
SCHEMBL9540520 0.82 HPGD (0.45) KMT2AMEN1TSHRHPGDGDA
SCHEMBL9538968 0.82 HPGD (0.43) KMT2AMEN1TSHRHPGDGDA
SCHEMBL9538971 0.82 HPGD (0.43) KMT2AMEN1TSHRHPGDGDA
SCHEMBL9540513 0.82 HPGD (0.45) KMT2AMEN1TSHRHPGDGDA
SCHEMBL9538872 0.82 HPGD (0.43) KMT2AMEN1TSHRHPGDGDA
SCHEMBL9540499 0.82 HPGD (0.45) KMT2AMEN1TSHRHPGDGDA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112608313-B Treatment method of mother liquor precipitate in production of triacetyl ganciclovir 河北合佳医药科技集团股份有限公司 2023-03-10 CN claimed
CN-112608313-A Treatment method of mother liquor precipitate in production of triacetyl ganciclovir 河北合佳医药科技集团股份有限公司 2021-04-06 CN claimed
EP-1565469-A1 PROCESS FOR THE SYNTHESIS OF GANCICLOVIR RANBAXY LABORATORIES, LTD. (IN) 2005-08-24 EP claimed
WO-2004048380-A1 PROCESS FOR THE SYNTHESIS OF GANCICLOVIR RANBAXY LABORATORIES LIMITED (IN) 2004-06-10 WO claimed
EP-0532878-A2 Process for producing acyclic nucleosides Ajinomoto Co., Inc. (JP) 1993-03-24 EP claimed
CN-112608313-B Treatment method of mother liquor precipitate in production of triacetyl ganciclovir 河北合佳医药科技集团股份有限公司 2023-03-10 CN disclosed
CN-112608313-B Treatment method of mother liquor precipitate in production of triacetyl ganciclovir 河北合佳医药科技集团股份有限公司 2023-03-10 CN disclosed
CN-112608313-A Treatment method of mother liquor precipitate in production of triacetyl ganciclovir 河北合佳医药科技集团股份有限公司 2021-04-06 CN disclosed
CN-112608313-A Treatment method of mother liquor precipitate in production of triacetyl ganciclovir 河北合佳医药科技集团股份有限公司 2021-04-06 CN disclosed
WO-2011114336-A1 PROCESS FOR THE ISOLATION OF GANCICLOVIR INTERMEDIATE HETERO RESEARCH FOUNDATION (IN) 2011-09-22 WO disclosed
EP-1565469-A1 PROCESS FOR THE SYNTHESIS OF GANCICLOVIR RANBAXY LABORATORIES, LTD. (IN) 2005-08-24 EP disclosed
EP-1453833-A2 A PROCESS FOR THE PREPARATION OF GANCICLOVIR INTERMEDIATE N2-ACETYL-9-(1,3-DIACETOXY-2-PROPOXYMETHYL) GUANINE RANBAXY LABORATORIES, LTD. (IN) 2004-09-08 EP disclosed
WO-2004048380-A1 PROCESS FOR THE SYNTHESIS OF GANCICLOVIR RANBAXY LABORATORIES LIMITED (IN) 2004-06-10 WO disclosed
WO-2003033498-A2 A PROCESS FOR THE TREATMENT OF GANCICLOVIR INTERMEDIATE N2-ACETYL-9-(1, 3-DIACETOXY-2-PROPOXYMETHYL) GUANINE RANBAXY LABORATORIES LIMITED (IN) 2003-04-24 WO disclosed
US-5583225-A REACTING N2, N9-DIPROTECTED GUANINE WITH DIACETOXYPROPANE IN THE PRESENCE OF A MIXTURE OF AN ACID AND ACETIC ANHYDRIDE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1996-12-10 US disclosed