Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536789 | 0.98 | TP53 (0.37) | SMN1; SMN2HSD17B10MAPK14TP53ACHE | |
| SCHEMBL10400778 | 0.94 | SMN1; SMN2 (0.40) | SMN1; SMN2HSD17B10MAPK14TP53ACHE | |
| SCHEMBL10517367 | 0.90 | TP53 (0.39) | SMN1; SMN2HSD17B10MAPK14TP53ACHE | |
| SCHEMBL10401290 | 0.88 | TP53 (0.41) | SMN1; SMN2HSD17B10MAPK14TP53ACHE | |
| SCHEMBL10400901 | 0.87 | MAPK14 (0.39) | SMN1; SMN2HSD17B10MAPK14TP53PRKD3 | |
| SCHEMBL10400225 | 0.86 | PRKD3 (0.39) | SMN1; SMN2HSD17B10MAPK14TP53ACHE | |
| SCHEMBL10400078 | 0.86 | HSD17B10 (0.39) | SMN1; SMN2HSD17B10TP53ACHEL3MBTL1 | |
| SCHEMBL10400075 | 0.84 | SMN1; SMN2 (0.35) | SMN1; SMN2HSD17B10MAPK14ACHEL3MBTL1 | |
| SCHEMBL10400944 | 0.84 | TSHR (0.37) | SMN1; SMN2HSD17B10MAPK14TP53ACHE | |
| SCHEMBL10401010 | 0.84 | SMN1; SMN2 (0.38) | SMN1; SMN2HSD17B10TP53L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337944-B1 | UREAS | CIBA-GEIGY AG (CH) | 1993-07-28 | — | — | EP | disclosed |
| US-4973690-A | PYRIMIDIN-2-YL UREAS, HERBICICES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1990-11-27 | — | — | US | disclosed |
| EP-0337944-A1 | Ureas | CIBA-GEIGY AG (CH) | 1989-10-18 | — | — | EP | disclosed |