Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 5/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 7/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | EEF2K | O00418 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10400745 | 0.98 | SMN1; SMN2 (0.36) | SMN1; SMN2L3MBTL1HSD17B10RAB9AHPGD | |
| SCHEMBL10517367 | 0.88 | TP53 (0.39) | SMN1; SMN2L3MBTL1HSD17B10HPGDALDH1A1 | |
| SCHEMBL10400778 | 0.87 | SMN1; SMN2 (0.40) | SMN1; SMN2L3MBTL1HSD17B10RAB9AHPGD | |
| SCHEMBL10401290 | 0.86 | TP53 (0.41) | SMN1; SMN2L3MBTL1HSD17B10ALDH1A1POLB | |
| SCHEMBL9538973 | 0.84 | SMN1; SMN2 (0.38) | SMN1; SMN2L3MBTL1HSD17B10RAB9ANPC1 | |
| SCHEMBL10400078 | 0.82 | HSD17B10 (0.39) | SMN1; SMN2L3MBTL1HSD17B10HPGDALDH1A1 | |
| SCHEMBL9536789 | 0.82 | TP53 (0.37) | SMN1; SMN2L3MBTL1HSD17B10HPGDALDH1A1 | |
| SCHEMBL10401003 | 0.82 | L3MBTL1 (0.38) | SMN1; SMN2L3MBTL1HSD17B10HPGDALDH1A1 | |
| SCHEMBL10400891 | 0.81 | ACHE (0.35) | SMN1; SMN2RAB9ANPC1KDM4ETP53 | |
| SCHEMBL10400901 | 0.81 | MAPK14 (0.39) | SMN1; SMN2HSD17B10ALDH1A1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4973690-A | PYRIMIDIN-2-YL UREAS, HERBICICES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1990-11-27 | — | — | US | disclosed |
| EP-0337944-A1 | Ureas | CIBA-GEIGY AG (CH) | 1989-10-18 | — | — | EP | disclosed |