Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 14/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9059576 | 0.93 | CHRM3 (0.44) | CHRM3ALDH1A1KMT2A | |
| SCHEMBL9059409 | 0.92 | CHRM3 (0.47) | CHRM3KDM1AMAOAMAOBKDM4E | |
| Fumaric Acid SCHEMBL9312680 | 0.84 | KDM4E (0.45) | CHRM3KDM4EALDH1A1KMT2A | |
| Fumaric Acid SCHEMBL9311361 | 0.83 | CHRM3 (0.46) | CHRM3KDM1AMAOAMAOBKDM4E | |
| SCHEMBL9059607 | 0.79 | CHRM3 (0.47) | CHRM3ALDH1A1KMT2A | |
| SCHEMBL9059897 | 0.79 | ALDH1A1 (0.49) | CHRM3KDM4EALDH1A1KMT2A | |
| SCHEMBL9059781 | 0.77 | CHRM3 (0.53) | CHRM3KDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL9059673 | 0.76 | CHRM3 (0.49) | CHRM3ALDH1A1KMT2A | |
| SCHEMBL9059856 | 0.75 | CHRM3 (0.53) | CHRM3KDM1AMAOAMAOBKDM4E | |
| SCHEMBL9536114 | 0.73 | CHRM3 (0.47) | CHRM3KDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536151-A1 | ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM. | BOOTS CO PLC (GB) | 1993-04-14 | — | — | EP | disclosed |