Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PDE6D | O43924 | 2/20 | 0.47 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11160756 | 0.80 | ALDH1A1 (0.51) | ALDH1A1LMNASMN1; SMN2RECQLRAB9A | |
| SCHEMBL11097622 | 0.74 | ALDH1A1 (0.56) | ALDH1A1LMNASMN1; SMN2RECQLRAB9A | |
| SCHEMBL6202033 | 0.72 | ALDH1A1 (0.50) | ALDH1A1LMNASMN1; SMN2RECQLRAB9A | |
| SCHEMBL11163273 | 0.72 | ALDH1A1 (0.59) | ALDH1A1LMNASMN1; SMN2RECQLRAB9A | |
| SCHEMBL11093772 | 0.72 | ALDH1A1 (0.59) | ALDH1A1LMNASMN1; SMN2RECQLRAB9A | |
| SCHEMBL6631450 | 0.72 | KMT2A (0.49) | ALDH1A1LMNASMN1; SMN2RECQLRAB9A | |
| SCHEMBL9441669 | 0.71 | ALDH1A1 (0.41) | ALDH1A1NPSR1KDM4EMEN1KMT2A | |
| SCHEMBL11098803 | 0.69 | IDO1 (0.43) | ALDH1A1LMNASMN1; SMN2RECQLRAB9A | |
| SCHEMBL20568381 | 0.69 | PDE5A (0.41) | ALDH1A1LMNASMN1; SMN2RAB9APDE6D | |
| SCHEMBL647666 | 0.69 | TSHR (0.48) | ALDH1A1SMN1; SMN2HPGDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993002089-A1 | KETOPHOSPHANATE COUPLING PROCEDURE | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-02-04 | — | — | WO | claimed |
| WO-1993002089-A1 | KETOPHOSPHANATE COUPLING PROCEDURE | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-02-04 | — | — | WO | disclosed |