Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 6/20 | 0.49 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | IDH2 | P48735 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9059324 | 0.82 | TDP1 (0.46) | FABP4NPSR1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL9311252 | 0.81 | FABP4 (0.49) | FABP4NPSR1KDM4EALDH1A1HPGD | |
| SCHEMBL9310567 | 0.80 | CHRM3 (0.47) | NPSR1KDM4EALDH1A1L3MBTL1GAA | |
| Iodide SCHEMBL11164020 | 0.78 | FABP4 (0.51) | FABP4FABP5NPSR1KDM4EALDH1A1 | |
| SCHEMBL5213164 | 0.77 | KDM4E (0.59) | FABP4FABP5NPSR1KDM4EALDH1A1 | |
| SCHEMBL5099112 | 0.76 | FABP4 (0.62) | FABP4FABP5NPSR1KDM4EALDH1A1 | |
| SCHEMBL11160989 | 0.74 | FABP4 (0.52) | FABP4FABP5KDM4EALDH1A1IRAK4 | |
| SCHEMBL23609610 | 0.73 | FABP4 (0.48) | FABP4FABP5NPSR1KDM4EALDH1A1 | |
| Fumaric Acid SCHEMBL9311538 | 0.73 | CHRM3 (0.46) | NPSR1KDM4EALDH1A1L3MBTL1GAA | |
| SCHEMBL21030832 | 0.73 | KCNMA1 (0.68) | FABP4FABP5NPSR1KDM4EIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536151-A1 | ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM. | BOOTS CO PLC (GB) | 1993-04-14 | — | — | EP | disclosed |