Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | NQO1 | P15559 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD5 | P21918 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539653 | 0.95 | USP2 (0.55) | KDM4EMAOBNQO1POLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9542152 | 0.89 | KDM4E (0.50) | KDM4EMAOBNQO1POLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9539560 | 0.89 | KDM4E (0.50) | KDM4EMAOBNQO1POLBL3MBTL1 | |
| SCHEMBL9539543 | 0.88 | KDM4E (0.47) | KDM4EPOLBSMN1; SMN2ESR1 | |
| Hydrochloric Acid SCHEMBL9539599 | 0.84 | NQO1 (0.53) | KDM4ENQO1POLBL3MBTL1USP2 | |
| Hydrochloric Acid SCHEMBL9538679 | 0.84 | NQO1 (0.53) | KDM4ENQO1POLBL3MBTL1USP2 | |
| SCHEMBL9540760 | 0.83 | ALDH1A1 (0.51) | KDM4ENQO1POLBL3MBTL1 | |
| SCHEMBL9542165 | 0.82 | KDM4E (0.56) | KDM4EMAOBNQO1POLBL3MBTL1 | |
| SCHEMBL9542150 | 0.80 | KDM4E (0.52) | KDM4EMAOBPOLBL3MBTL1USP2 | |
| Hydrochloric Acid SCHEMBL9538671 | 0.77 | AURKA (0.51) | KDM4EPOLBSMN1; SMN2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993005054-A1 | OXAZAPHOSPHORINES USEFUL AS ANTITUMOR AGENTS, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-03-18 | — | — | WO | disclosed |