Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | NQO1 | P15559 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TERT | O14746 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | WEE1 | P30291 | 3/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539615 | 0.95 | KDM4E (0.55) | USP2NQO1KDM4EPOLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9539599 | 0.90 | NQO1 (0.53) | USP2NQO1KDM4EPOLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9538679 | 0.90 | NQO1 (0.53) | USP2NQO1KDM4EPOLBL3MBTL1 | |
| SCHEMBL9540760 | 0.88 | ALDH1A1 (0.51) | NQO1KDM4EPOLBL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9542152 | 0.84 | KDM4E (0.50) | USP2NQO1KDM4EPOLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9539560 | 0.84 | KDM4E (0.50) | USP2NQO1KDM4EPOLBL3MBTL1 | |
| SCHEMBL9539543 | 0.83 | KDM4E (0.47) | KDM4EPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL9540713 | 0.82 | USP2 (0.57) | USP2NQO1KDM4EPOLBL3MBTL1 | |
| SCHEMBL9539407 | 0.81 | USP2 (0.53) | USP2KDM4EPOLBL3MBTL1CYP1A2 | |
| Hydrochloric Acid SCHEMBL9539440 | 0.78 | AURKA (0.50) | NQO1KDM4EPOLBL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993005054-A1 | OXAZAPHOSPHORINES USEFUL AS ANTITUMOR AGENTS, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-03-18 | — | — | WO | disclosed |