Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 4/20 | 0.57 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.57 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538808 | 0.76 | ALOX5 (0.56) | SLC1A3SLC1A2SLC1A1ALOX5PTGS1 | |
| SCHEMBL9539663 | 0.76 | SLC1A3 (0.57) | SLC1A3SLC1A2SLC1A1ALOX5CYP2C19 | |
| SCHEMBL9541349 | 0.73 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1ALOX5OPRM1 | |
| SCHEMBL9377194 | 0.73 | ALOX5 (0.51) | SLC1A3SLC1A2SLC1A1ALOX5 | |
| SCHEMBL9374441 | 0.73 | ALOX5 (0.60) | SLC1A3SLC1A2SLC1A1ALOX5DPP4 | |
| Potassium SCHEMBL9373808 | 0.71 | ALOX5 (0.50) | SLC1A3SLC1A2SLC1A1ALOX5 | |
| SCHEMBL8689056 | 0.71 | SLC1A3 (0.53) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 | |
| SCHEMBL9584897 | 0.70 | ALOX5 (0.56) | SLC1A3SLC1A2SLC1A1ALOX5MEN1 | |
| SCHEMBL9539758 | 0.70 | ALOX5 (0.58) | ALOX5 | |
| SCHEMBL9372981 | 0.70 | ALOX5 (0.49) | SLC1A3SLC1A2SLC1A1ALOX5DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003719-A1 | ARYLALKYLETHER AND ARYLALKYLTHIOETHER INHIBITORS OF LIPOXYGENASE ENZYME ACTIVITY | ABBOTT LABORATORIES (US) | 1993-03-04 | — | — | WO | claimed |
| WO-1993003719-A1 | ARYLALKYLETHER AND ARYLALKYLTHIOETHER INHIBITORS OF LIPOXYGENASE ENZYME ACTIVITY | ABBOTT LABORATORIES (US) | 1993-03-04 | — | — | WO | disclosed |
| US-5183818-A | Also for inhibiting leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1993-02-02 | — | — | US | disclosed |