Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9372981 | 0.80 | ALOX5 (0.49) | SLC1A3SLC1A2SLC1A1ALOX5TAAR1 | |
| SCHEMBL9373218 | 0.77 | ALOX5 (0.47) | SLC1A3SLC1A2SLC1A1ALOX5LTA4H | |
| SCHEMBL9377194 | 0.76 | ALOX5 (0.51) | SLC1A3SLC1A2SLC1A1ALOX5TAAR1 | |
| Potassium SCHEMBL9373808 | 0.74 | ALOX5 (0.50) | SLC1A3SLC1A2SLC1A1ALOX5TAAR1 | |
| SCHEMBL9542445 | 0.73 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1ALOX5MMP2 | |
| SCHEMBL9539696 | 0.73 | ALOX5 (0.60) | SLC1A3SLC1A2SLC1A1ALOX5MMP2 | |
| SCHEMBL9539698 | 0.73 | SLC1A3 (0.57) | SLC1A3SLC1A2SLC1A1ALOX5OPRM1 | |
| SCHEMBL20912421 | 0.73 | SLC1A3 (0.49) | SLC1A3SLC1A2SLC1A1LTA4HTAAR1 | |
| SCHEMBL8905224 | 0.73 | SLC1A3 (0.44) | SLC1A3SLC1A2SLC1A1LTA4HTAAR1 | |
| SCHEMBL8689058 | 0.72 | SLC1A3 (0.42) | SLC1A3SLC1A2SLC1A1LTA4HTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003719-A1 | ARYLALKYLETHER AND ARYLALKYLTHIOETHER INHIBITORS OF LIPOXYGENASE ENZYME ACTIVITY | ABBOTT LABORATORIES (US) | 1993-03-04 | — | — | WO | claimed |
| WO-1993003719-A1 | ARYLALKYLETHER AND ARYLALKYLTHIOETHER INHIBITORS OF LIPOXYGENASE ENZYME ACTIVITY | ABBOTT LABORATORIES (US) | 1993-03-04 | — | — | WO | disclosed |
| US-5183818-A | Also for inhibiting leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1993-02-02 | — | — | US | disclosed |