Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.47 |
| ▸ | BCHE | P06276 | 10/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL9539705 | 0.83 | ACHE (0.42) | ACHEBCHEHPGDLMNAMAPT | |
| SCHEMBL9537208 | 0.80 | ACHE (0.44) | ACHEBCHEHPGDHSD17B10KDM4E | |
| SCHEMBL9536742 | 0.78 | BCHE (0.43) | ACHEBCHEHPGDHSD17B10KDM4E | |
| SCHEMBL9541181 | 0.77 | BCHE (0.42) | ACHEBCHEHPGDHSD17B10KDM4E | |
| SCHEMBL9538273 | 0.76 | BCHE (0.54) | ACHEBCHE | |
| SCHEMBL9538866 | 0.76 | BCHE (0.41) | ACHEBCHEHPGDHSD17B10KDM4E | |
| SCHEMBL9538106 | 0.74 | ACHE (0.41) | ACHEBCHECYP1A2MAPTCYP2C19 | |
| SCHEMBL9537564 | 0.69 | ACHE (0.51) | ACHEBCHELMNACYP1A2MAPT | |
| SCHEMBL12081151 | 0.64 | ACHE (1.00) | ACHEBCHEMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14243157 | 0.64 | ACHE (1.00) | ACHEBCHEMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5187165-A | Eseroline derivatives; cholinergic agents; antidepressants | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-02-16 | — | — | US | disclosed |