Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 18/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | IARS1 | P41252 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9584855 | 0.78 | ALOX5 (0.52) | ALOX5 | |
| SCHEMBL9539738 | 0.73 | ALOX5 (0.61) | ALOX5MMP2 | |
| SCHEMBL9542469 | 0.72 | ALOX5 (0.60) | ALOX5MMP2 | |
| SCHEMBL9832426 | 0.70 | ALOX5 (0.71) | ALOX5 | |
| SCHEMBL9539727 | 0.69 | ALOX5 (0.56) | ALOX5 | |
| SCHEMBL8807791 | 0.69 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9539758 | 0.69 | ALOX5 (0.58) | ALOX5 | |
| SCHEMBL8806921 | 0.68 | ALOX5 (0.97) | ALOX5 | |
| Ammonia Solution, Strong SCHEMBL8807165 | 0.68 | ALOX5 (0.97) | ALOX5 | |
| SCHEMBL24892070 | 0.68 | TDP1 (0.40) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003719-A1 | ARYLALKYLETHER AND ARYLALKYLTHIOETHER INHIBITORS OF LIPOXYGENASE ENZYME ACTIVITY | ABBOTT LABORATORIES (US) | 1993-03-04 | — | — | WO | disclosed |
| US-5183818-A | Also for inhibiting leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1993-02-02 | — | — | US | disclosed |