Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539738 | 0.87 | ALOX5 (0.61) | ALOX5MAPTMMP2ALDH1A1PKM | |
| SCHEMBL9832426 | 0.85 | ALOX5 (0.71) | ALOX5KDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL9539727 | 0.77 | ALOX5 (0.56) | ALOX5KDM4EMAPTESR2MEN1 | |
| SCHEMBL8809759 | 0.76 | ALOX5 (1.00) | ALOX5PKMPOLB | |
| Tetrabuthylammonium SCHEMBL9833807 | 0.74 | ALOX5 (0.55) | ALOX5KDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL9539795 | 0.72 | ALOX5 (0.52) | ALOX5MMP2 | |
| SCHEMBL9832912 | 0.71 | ALOX5 (0.43) | ALOX5MAPTMMP2MEN1KMT2A | |
| SCHEMBL9585668 | 0.70 | ALOX5 (0.49) | ALOX5KDM4EMAPTMMP2MEN1 | |
| SCHEMBL9832106 | 0.70 | ALOX5 (0.53) | ALOX5KDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL9584883 | 0.69 | ALOX5 (0.62) | ALOX5KDM4EMAPTMMP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003719-A1 | ARYLALKYLETHER AND ARYLALKYLTHIOETHER INHIBITORS OF LIPOXYGENASE ENZYME ACTIVITY | ABBOTT LABORATORIES (US) | 1993-03-04 | — | — | WO | claimed |