Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540047 | 0.88 | PGR (0.40) | PGRAKR1B1CHRM1MEN1KMT2A | |
| SCHEMBL9539805 | 0.86 | PGR (0.41) | PGRAKR1B1CHRM1MEN1KMT2A | |
| SCHEMBL9539937 | 0.84 | CHRM1 (0.41) | PGRAKR1B1CHRM1MEN1KMT2A | |
| SCHEMBL9539997 | 0.83 | PGR (0.39) | PGRAKR1B1CHRM1CYP2D6MAPT | |
| SCHEMBL9539803 | 0.82 | PGR (0.38) | PGRAKR1B1CHRM1OPRM1KDM4E | |
| SCHEMBL9540169 | 0.82 | IDO1 (0.41) | PGRAKR1B1MEN1TP53KMT2A | |
| SCHEMBL9540123 | 0.82 | PGR (0.43) | PGRAKR1B1CHRM1MEN1KMT2A | |
| SCHEMBL9541572 | 0.80 | PGR (0.37) | PGRAKR1B1CHRM1MEN1KMT2A | |
| SCHEMBL9539988 | 0.79 | PGR (0.36) | PGRAKR1B1CHRM1OPRM1MAPT | |
| SCHEMBL9542738 | 0.79 | PGR (0.36) | PGRAKR1B1CHRM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530994-A1 | Quinazoline derivatives as inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1993-03-10 | — | — | EP | disclosed |
| WO-1993004047-A1 | QUINAZOLINE DERIVATIVES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE | MERCK & CO., INC. (US) | 1993-03-04 | — | — | WO | disclosed |