SCHEMBL5008947

SCHEMBL5008947

Cl[Si](c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.39
ALDH1A1 P00352 5/20 0.35
LMNA P02545 2/20 0.33
BBOX1 O75936 1/20 0.33
EHMT2 Q96KQ7 1/20 0.33
EHMT1 Q9H9B1 1/20 0.33
TRPA1 O75762 1/20 0.33
APOBEC3A P31941 1/20 0.32
APOBEC3G Q9HC16 1/20 0.32
ORAI1 Q96D31 1/20 0.32
ORAI2 Q96SN7 1/20 0.32
ORAI3 Q9BRQ5 1/20 0.32
TRPV6 Q9H1D0 1/20 0.32
CYP1A2 P05177 1/20 0.32
TDP1 Q9NUW8 3/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
CA12 O43570 1/20 0.32
GLA P06280 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3666913 0.79
SCHEMBL3315510 0.73
SCHEMBL1778033 0.69 ALDH1A1 (0.40) TSHRALDH1A1LMNABBOX1EHMT2
SCHEMBL38901 0.69 ALDH1A1 (0.40) TSHRALDH1A1LMNABBOX1EHMT2
SCHEMBL9540158 0.67 TP53 (0.38) TSHRALDH1A1LMNATRPA1ALOX12
Phosphine SCHEMBL29078666 0.67 ALDH1A1 (0.38) TSHRALDH1A1LMNABBOX1EHMT2
Fluoride SCHEMBL28572273 0.67 ALDH1A1 (0.38) TSHRALDH1A1LMNABBOX1EHMT2
SCHEMBL21838773 0.67 ALDH1A1 (0.38) TSHRALDH1A1LMNABBOX1EHMT2
SCHEMBL28546150 0.67 ALDH1A1 (0.38) TSHRALDH1A1LMNABBOX1EHMT2
Hydrochloric Acid SCHEMBL6905007 0.67 ALDH1A1 (0.38) TSHRALDH1A1LMNABBOX1EHMT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250011621-A1 COMPOSITE COATING, PREPARATION METHOD, AND DEVICE JIANGSU FAVORED NANOTECHNOLOGY CO., LTD. (CN) 2025-01-09 US disclosed
EP-4451832-A2 HETEROAROMATIC COMPOUNDS Merck Patent GmbH (DE) 2024-10-23 EP disclosed
EP-3728275-B1 HETEROAROMATIC COMPOUNDS MERCK PATENT GMBH (DE) 2024-09-04 EP disclosed
EP-4350031-A1 PLASMA POLYMERISATION COATING, PREPARATION METHOD, AND DEVICE Jiangsu Favored Nanotechnology Co., Ltd. (CN) 2024-04-10 EP disclosed
CN-117568000-B Differential pressure plugging agent and preparation process thereof 东营市汇友石油新技术开发有限责任公司 2024-03-29 CN disclosed
CN-117568000-A Differential pressure plugging agent and preparation process thereof 东营市汇友石油新技术开发有限责任公司 2024-02-20 CN disclosed
CN-115991951-B Composite coating, preparation method and device 江苏菲沃泰纳米科技股份有限公司 2024-02-20 CN disclosed
CN-116606261-A KRAS G12C inhibitors and methods of use thereof 美国安进公司 2023-08-18 CN disclosed
WO-2023066103-A1 COMPOSITE COATING, PREPARATION METHOD, AND DEVICE 江苏菲沃泰纳米科技股份有限公司 2023-04-27 WO disclosed
CN-115991951-A Composite coating, preparation method and device 江苏菲沃泰纳米科技股份有限公司 2023-04-21 CN disclosed
WO-2003035708-A1 SOLID COCATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST SYSTEM THEREOF SUNALLOMER LTD (JP) 2003-05-01 WO disclosed
EP-0775707-B1 Ionic compounds and catalyst for olefin polymerisation using the compounds SHOWA DENKO KK (JP) 2001-11-28 EP disclosed
US-5869723-A PRODUCING HIGHLY ACTIVE POLYMER WHICH DOES NOT ATTACH TO INNER WALL OF REACTOR SHOWA DENKO K.K. (JP) 1999-02-09 US disclosed
EP-0775707-A1 IONIC COMPOUNDS AND CATALYST FOR OLEFIN POLYMERIZATION USING THE COMPOUNDS SHOWA DENKO KABUSHIKI KAISHA (JP) 1997-05-28 EP disclosed
EP-0497171-B1 Polycarbosilanes containing heteroatoms SOLVAY DEUTSCHLAND (DE) 1997-04-02 EP disclosed
EP-0375994-B1 Process for preparing polycarbosilanes; polycarbosilanes obtained by this process KALI CHEMIE AG (DE) 1994-03-16 EP disclosed
US-5204431-A POLYCARBOSILANES CONTAINING A HETERO ELEMENT SOLVAY DEUTSCHLAND, GMBH (DE) 1993-04-20 US disclosed
EP-0497171-A2 Polycarbosilanes containing heteroatoms Solvay Deutschland GmbH (DE) 1992-08-05 EP disclosed
US-5087685-A PROCESS FOR PREPARING POLYCARBOSILANES AND NEW POLYCARBOSILANES KALI-CHEMIE AKTIENGESELLSCHAFT (DE) 1992-02-11 US disclosed
EP-0375994-A1 Process for preparing polycarbosilanes; polycarbosilanes obtained by this process Kali-Chemie Aktiengesellschaft (DE) 1990-07-04 EP disclosed