Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18795490 | 0.82 | MAPT (0.47) | ALDH1A1HPGDKMT2AMAPTSLC6A4 | |
| SCHEMBL9541376 | 0.82 | ALDH1A1 (0.60) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL9540333 | 0.77 | HPGD (0.72) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL9464523 | 0.77 | ALDH1A1 (0.72) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL9660771 | 0.75 | ALDH1A1 (0.55) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL8534092 | 0.75 | ALDH1A1 (0.69) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL9540270 | 0.74 | ALDH1A1 (0.64) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL1647150 | 0.74 | MEN1 (0.52) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL8530329 | 0.71 | ALDH1A1 (0.50) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL9206778 | 0.71 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993012080-A1 | SUBSTITUTED DIPHENYLSULFIDES AS SEROTONIN UPTAKE INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-06-24 | — | — | WO | disclosed |