Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.39 |
| ▸ | ITGAL | P20701 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464523 | 0.90 | ALDH1A1 (0.72) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9540270 | 0.87 | ALDH1A1 (0.64) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8535263 | 0.81 | ALDH1A1 (1.00) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8534092 | 0.78 | ALDH1A1 (0.69) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9541386 | 0.78 | ALDH1A1 (0.66) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9541381 | 0.78 | ALDH1A1 (0.66) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9660771 | 0.78 | ALDH1A1 (0.55) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11531926 | 0.77 | HPGD (0.51) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9540329 | 0.77 | ALDH1A1 (0.54) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9541376 | 0.76 | ALDH1A1 (0.60) | HPGDALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993012080-A1 | SUBSTITUTED DIPHENYLSULFIDES AS SEROTONIN UPTAKE INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-06-24 | — | — | WO | disclosed |