Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 3/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | AKT1S1 | Q96B36 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539598 | 0.80 | SLC6A4 (0.39) | PDE2AFFAR1 | |
| SCHEMBL9542135 | 0.77 | SLC6A2 (0.45) | FFAR1 | |
| SCHEMBL17064823 | 0.77 | FFAR1 (0.36) | FFAR1 | |
| SCHEMBL9539605 | 0.77 | FFAR1 (0.49) | FFAR1 | |
| SCHEMBL9539582 | 0.75 | RPS6KB1 (0.39) | PDE2ARPS6KB1FFAR2CES2CES1 | |
| SCHEMBL2652751 | 0.75 | TRPV3 (0.46) | RPS6KB1TRPV3FFAR1 | |
| SCHEMBL2652705 | 0.75 | TRPV3 (0.46) | RPS6KB1TRPV3FFAR1 | |
| SCHEMBL19120894 | 0.74 | PDE2A (0.41) | PDE2ARPS6KB1AKT1S1 | |
| SCHEMBL10989062 | 0.73 | SLC6A4 (0.44) | — | |
| SCHEMBL20790946 | 0.73 | PDE2A (0.41) | PDE2AFFAR2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223536-A | Pyrethroid-like pesticides | FMC CORPORATION (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993001715-A1 | 1,4-DIARYL-1-CYCLOPROPYL-4-SUBSTITUTED BUTANES AS INSECTICIDES AND ACARICIDES | FMC CORPORATION (US) | 1993-02-04 | — | — | WO | disclosed |