Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | EDNRA | P25101 | 1/20 | 0.58 |
| ▸ | RXRA | P19793 | 2/20 | 0.55 |
| ▸ | RXRB | P28702 | 1/20 | 0.55 |
| ▸ | RXRG | P48443 | 1/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.55 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | HPD | P32754 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2331143 | 0.88 | MAPT (0.65) | PTGER1MAPTTDP1L3MBTL1MAPK1 | |
| SCHEMBL9540402 | 0.87 | L3MBTL1 (0.67) | PTGER1MAPTTDP1L3MBTL1MAPK1 | |
| SCHEMBL16319063 | 0.86 | L3MBTL1 (0.63) | PTGER1MAPTTDP1L3MBTL1MAPK1 | |
| SCHEMBL25720776 | 0.86 | MAPT (0.63) | PTGER1MAPTTDP1L3MBTL1MAPK1 | |
| SCHEMBL29433417 | 0.84 | SGMS2 (0.66) | PTGER1MAPTL3MBTL1SGMS2FOLH1 | |
| SCHEMBL112903 | 0.84 | SGMS2 (0.66) | PTGER1MAPTL3MBTL1SGMS2FOLH1 | |
| Bicarbonate SCHEMBL236872 | 0.83 | SGMS2 (0.64) | PTGER1MAPTL3MBTL1SGMS2FOLH1 | |
| Bicarbonate SCHEMBL21753662 | 0.83 | SGMS2 (0.64) | PTGER1MAPTL3MBTL1SGMS2FOLH1 | |
| Bicarbonate SCHEMBL29914194 | 0.83 | SGMS2 (0.64) | PTGER1MAPTL3MBTL1SGMS2FOLH1 | |
| Hydrochloric Acid SCHEMBL8998291 | 0.83 | SGMS2 (0.64) | PTGER1MAPTL3MBTL1SGMS2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0857713-B1 | Process for the preparation of 3-hydroxy- and 3-acetoxy-2-methylbenzoic acid | CLARIANT GMBH (DE) | 2001-06-13 | — | — | EP | claimed |
| US-5910605-A | Process for the preparation of 3-hydroxy-2-methylbenzoic acid and 3-acetoxy-2-methylbenzoic | CLARIANT GMBH (DE) | 1999-06-08 | — | — | US | claimed |
| EP-0857713-A1 | Process for the preparation of 3-hydroxy- and 3-acetoxy-2-methylbenzoic acid | Clariant GmbH (DE) | 1998-08-12 | — | — | EP | claimed |
| JP-10273475-A | — | — | None | — | — | JP | disclosed |
| CN-117794526-A | Compositions and methods for antioxidants and anti-inflammatory therapeutics | 阿万蒂生物科学股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-108101870-B | Preparation method of active ingredient for selectively treating glaucoma and related salt thereof | 盐城师范学院 | 2020-03-06 | — | — | CN | disclosed |
| CN-108101870-A | A kind of active ingredient of selective therapy glaucoma and its preparation method of associated salts | 盐城师范学院 | 2018-06-01 | — | — | CN | disclosed |
| US-20180111929-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC (US) | 2018-04-26 | — | — | US | disclosed |
| US-20180111929-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC (US) | 2018-04-26 | — | — | US | disclosed |
| US-20180111929-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC (US) | 2018-04-26 | — | — | US | disclosed |
| EP-3088400-A1 | PYRROLO[2,3-B]PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | PLEXXIKON INC. (US) | 2016-11-02 | — | — | EP | disclosed |
| WO-2007002325-A1 | PYRROLO[2,3-B] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | PLEXXIKON, INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-6284777-B1 | BONE DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2001-09-04 | — | — | US | disclosed |
| EP-0857713-B1 | Process for the preparation of 3-hydroxy- and 3-acetoxy-2-methylbenzoic acid | CLARIANT GMBH (DE) | 2001-06-13 | — | — | EP | disclosed |
| US-5910605-A | Process for the preparation of 3-hydroxy-2-methylbenzoic acid and 3-acetoxy-2-methylbenzoic | CLARIANT GMBH (DE) | 1999-06-08 | — | — | US | disclosed |
| US-5910605-A | Process for the preparation of 3-hydroxy-2-methylbenzoic acid and 3-acetoxy-2-methylbenzoic | CLARIANT GMBH (DE) | 1999-06-08 | — | — | US | disclosed |
| JP-H10273475-A | PRODUCTION OF 3-HYDROXY-2-METHYLBENZOIC ACID AND 3-ACETOXY-2-METHYLBENZOIC ACID | CLARIANT GMBH | 1998-10-13 | — | — | JP | disclosed |
| EP-0857713-A1 | Process for the preparation of 3-hydroxy- and 3-acetoxy-2-methylbenzoic acid | Clariant GmbH (DE) | 1998-08-12 | — | — | EP | disclosed |
| EP-0857713-A1 | Process for the preparation of 3-hydroxy- and 3-acetoxy-2-methylbenzoic acid | Clariant GmbH (DE) | 1998-08-12 | — | — | EP | disclosed |
| EP-0079168-B1 | PROCESS FOR MAKING 1-(3-BENZYLOXYPHENYL)-1,1-DIMETHYLHEPTANE AND INTERMEDIATES THEREFOR | PFIZER INC. (US) | 1984-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180111929-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | MAP3K20, MAP3K13, MAP3K8 | PTGER1 2394/4885MAPT 2203/4885TDP1 631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.