Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 2/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TACR2 | P21452 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL10551011 | 0.96 | TP53 (0.44) | SSTR5MCHR1KCNH2NR4A2HRH1 | |
| SCHEMBL9539265 | 0.90 | HRH1 (0.43) | SSTR5MCHR1KCNH2NR4A2HRH1 | |
| Oxalic Acid SCHEMBL10798151 | 0.89 | TP53 (0.46) | SSTR5MCHR1KCNH2NR4A2HRH1 | |
| Oxalic Acid SCHEMBL10798146 | 0.89 | TP53 (0.46) | SSTR5MCHR1KCNH2NR4A2HRH1 | |
| Oxalic Acid SCHEMBL9537634 | 0.89 | MCHR1 (0.42) | SSTR5MCHR1KCNH2NR4A2HRH1 | |
| Oxalic Acid SCHEMBL9537639 | 0.89 | MCHR1 (0.42) | SSTR5MCHR1KCNH2NR4A2HRH1 | |
| SCHEMBL10551189 | 0.88 | SSTR5 (0.47) | SSTR5KCNH2NR4A2HRH1TP53 | |
| SCHEMBL10550679 | 0.87 | RAB9A (0.46) | SSTR5MCHR1KCNH2NR4A2HRH1 | |
| SCHEMBL9539913 | 0.84 | RAB9A (0.45) | SSTR5MCHR1KCNH2NR4A2HRH1 | |
| Oxalic Acid SCHEMBL10552513 | 0.82 | SSTR5 (0.51) | SSTR5MCHR1KCNH2NR4A2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151826-B1 | 4-[(Bicyclic heterocyclyl)-methyl and -hetero]-piperidines | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-03-31 | — | — | EP | claimed |