SCHEMBL9540505

SCHEMBL9540505

C=CC(C)(C)COC([O])=O

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HIF1A Q16665 1/20 0.38
THRB P10828 1/20 0.32
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11444677 0.82 ALDH1A1 (0.39) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL9540509 0.82 ALDH1A1 (0.38) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL13864538 0.80 ALDH1A1 (0.36) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL28212376 0.80 ALDH1A1 (0.61) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL18269581 0.77 ALDH1A1 (0.52) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL23544374 0.75 TSHR (0.49) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL27480919 0.74 THRA (0.40) ALDH1A1THRBTSHR
SCHEMBL1462566 0.72
SCHEMBL23544378 0.70 TSHR (0.60) ALDH1A1TSHR
SCHEMBL9750842 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993011669-A1 USE OF 3-PHENYLURACIL DERIVATIVES FOR THE DESICCATION AND ABSCISSION OF PLANT PARTS BASF AKTIENGESELLSCHAFT (DE) 1993-06-24 WO disclosed