SCHEMBL9540535

SCHEMBL9540535

C=C(C)[CH]Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.48
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
ARG2 P78540 1/20 0.42
ALDH1A1 P00352 2/20 0.39
TP53 P04637 1/20 0.39
TSHR P16473 1/20 0.39
NOS2 P35228 2/20 0.38
LMNA P02545 1/20 0.36
NOS1 P29475 1/20 0.36
CALM1 P0DP23 1/20 0.36
TDP1 Q9NUW8 2/20 0.36
CYP2C19 P33261 1/20 0.35
TOP1 P11387 1/20 0.35
GAA P10253 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19097614 0.88 TAAR1 (0.42) MAOBALDH1A1TSHRLMNAGAA
SCHEMBL11498025 0.78 MAOB (0.56) MAOBCA1CA2ARG2ALDH1A1
SCHEMBL3244969 0.77 ALDH1A1 (0.48) MAOBCA1CA2ARG2ALDH1A1
SCHEMBL6951831 0.74 MAOB (0.44) MAOBCA1CA2ARG2ALDH1A1
SCHEMBL28779127 0.74 ALOX15 (0.47) MAOBCA1CA2ARG2ALDH1A1
SCHEMBL4645707 0.74 ALDH1A1 (0.48) MAOBALDH1A1TSHRLMNACYP2C19
SCHEMBL294028 0.72 MAOB (0.43) MAOBCA1CA2ALDH1A1TSHR
SCHEMBL1586710 0.71 MAOB (0.52) MAOBCA1CA2ARG2ALDH1A1
SCHEMBL6891100 0.71 MAOB (0.52) MAOBCA1CA2ARG2ALDH1A1
SCHEMBL9327534 0.71 MAOB (0.52) MAOBCA1CA2ARG2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993001246-A1 REAGENT KIT FOR THE PRODUCTION OF SYNTHETIC-RESIN ELEMENTS FOR BONDING FIXATION ELEMENTS IN PLACE IN AN ATTACHMENT SURFACE UPAT GMBH & CO. (DE) 1993-01-21 WO claimed