Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 2/20 | 0.58 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743749 | 0.88 | KCNA5 (0.56) | KCNA5MALT1BCHENQO2HCRTR1 | |
| SCHEMBL28027633 | 0.87 | KCNA5 (0.56) | KCNA5MALT1BCHENQO2HCRTR1 | |
| SCHEMBL4059012 | 0.83 | HPGD (0.56) | KCNA5MALT1BCHEHCRTR1IDO1 | |
| SCHEMBL1657927 | 0.82 | ESRRG (0.56) | KCNA5MALT1BCHEHCRTR1IDO1 | |
| SCHEMBL14690580 | 0.80 | CRBN (0.51) | KCNA5MALT1BCHEHCRTR1IDO1 | |
| SCHEMBL7654695 | 0.79 | KCNA5 (0.54) | KCNA5MALT1BCHENQO2IDO1 | |
| SCHEMBL24086511 | 0.78 | NQO2 (0.53) | KCNA5MALT1BCHENQO2IDO1 | |
| SCHEMBL9540579 | 0.77 | KCNA5 (0.43) | KCNA5KMT2ANPC1RAB9ALMNA | |
| SCHEMBL1754810 | 0.77 | POLB (0.58) | MALT1BCHEIDO1NPC1RAB9A | |
| SCHEMBL319240 | 0.76 | ALDH1A1 (0.45) | KCNA5HTTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993000906-A1 | MUSCARINIC ANTAGONISTS | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1993-01-21 | — | — | WO | disclosed |