Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9430861 | 0.78 | EPHX2 (0.39) | LTA4HNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL9540574 | 0.77 | KCNA5 (0.58) | KCNA5NPC1RAB9ALMNAKMT2A | |
| SCHEMBL5664578 | 0.73 | EPHX2 (0.46) | LTA4HHPGDKDM4EALDH1A1GAA | |
| SCHEMBL4495372 | 0.73 | EPHX2 (0.48) | POLBHPGDKDM4EALDH1A1LMNA | |
| SCHEMBL319240 | 0.72 | ALDH1A1 (0.45) | KCNA5NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL30736662 | 0.72 | ALDH1A1 (0.45) | KCNA5NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL5663152 | 0.72 | MLYCD (0.40) | HPGDKDM4EALDH1A1KMT2A | |
| SCHEMBL5663894 | 0.72 | GAA (0.50) | PRMT5SMN1; SMN2GAAKMT2A | |
| SCHEMBL6500075 | 0.71 | SYK (0.61) | LTA4HSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL1980813 | 0.71 | L3MBTL1 (0.53) | HPGDKDM4EALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993000906-A1 | MUSCARINIC ANTAGONISTS | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1993-01-21 | — | — | WO | disclosed |