SCHEMBL9540596

SCHEMBL9540596

CC(F)(C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
THRB P10828 1/20 0.33
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9541121 0.96 LMNA (0.39) LMNATHRB
SCHEMBL8156541 0.92 LMNA (0.44) LMNATHRBCA2
SCHEMBL9538325 0.92 LMNA (0.44) LMNATHRBCA2
SCHEMBL1760679 0.91 LMNA (0.33) LMNA
SCHEMBL3287279 0.89 LMNA (0.35) LMNA
SCHEMBL10534900 0.89 LMNA (0.35) LMNA
SCHEMBL37683 0.87 LMNA (0.39) LMNATHRB
Perflubutane SCHEMBL30040917 0.85 LMNA (0.50) LMNATHRBCA2
SCHEMBL9538354 0.84 LMNA (0.44) LMNATHRBCA2
SCHEMBL9535929 0.84 LMNA (0.37) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993005200-A1 AZEOTROPE-LIKE COMPOSITIONS OF 1,1-DICHLORO-1-FLUOROETHANE AND PERFLUOROCARBONS AND OPTIONALLY NITROMETHANE ALLIED-SIGNAL INC. (US) 1993-03-18 WO disclosed