SCHEMBL1760679

SCHEMBL1760679

CC(F)(C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9541121 0.96 LMNA (0.39) LMNA
SCHEMBL9538325 0.92 LMNA (0.44) LMNA
SCHEMBL8156541 0.92 LMNA (0.44) LMNA
SCHEMBL9538350 0.91 LMNA (0.33) LMNA
SCHEMBL9540596 0.91 LMNA (0.41) LMNA
SCHEMBL9540339 0.89
SCHEMBL4977272 0.87 LMNA (0.32) LMNA
SCHEMBL18116300 0.84 LMNA (0.30) LMNA
SCHEMBL9536920 0.84 LMNA (0.30) LMNA
SCHEMBL18135328 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12540073-B2 Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor BRILLIANT LIGHT POWER, INC. (US) 2026-02-03 US disclosed
US-20230045778-A9 HETEROGENEOUS HYDROGEN-CATALYST SOLID FUEL REACTION MIXTURE AND REACTOR BRILLIANT LIGHT POWER, INC. (US) 2023-02-09 US disclosed
US-20200299130-A1 HETEROGENEOUS HYDROGEN-CATALYST REACTOR BRILLIANT LIGHT POWER, INC. (US) 2020-09-24 US disclosed
EP-3038622-B1 HETEROCYCLIC COMPOUNDS AND METHODS OF USE MEDIVATION TECH LLC (US) 2018-05-30 EP disclosed
US-9670172-B2 Heterocyclic compounds and methods of use MEDIVATION TECHNOLOGIES, INC. (US) 2017-06-06 US disclosed
WO-2015031650-A1 HETEROCYCLIC COMPOUNDS AND METHODS OF USE CHAKRAVARTY SARVAJIT (US) 2015-03-05 WO disclosed
US-20150065519-A1 HETEROCYCLIC COMPOUNDS AND METHODS OF USE MEDIVATION TECHNOLOGIES LLC 2015-03-05 US disclosed
US-8273152-B2 Separation method and apparatus PRAXAIR TECHNOLOGY, INC. (US) 2012-09-25 US disclosed
US-20110114075-A1 HETEROGENEOUS HYDROGEN-CATALYST REACTOR BRILLIANT LIGHT POWER, INC. 2011-05-19 US disclosed
EP-2318307-A2 HETEROGENEOUS HYDROGEN-CATALYST REACTOR Blacklight Power, Inc. (US) 2011-05-11 EP disclosed
US-5721285-A CLOSED-CELL POLYURETHANE FOAMS COMPRISING A VOLATILE COMPOUND, A SOLID OR LIQUID CYCLIC CARBONATE REACTION PRODUCT OF CARBON DIOXIDE AND EPOXY COMPOUND; FOAMS USING IN REFRIGERATOR AND FREEZER MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1998-02-24 US disclosed
EP-0575543-B1 FOAMING SYSTEM FOR RIGID URETHANE AND ISOCYANURATE FOAMS DOW CHEMICAL CO (US) 1997-04-23 EP disclosed
EP-0723989-A2 Thermal insulating foamed material and method of manufacturing the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1996-07-31 EP disclosed
EP-0679681-A1 Heat insulating foamed material and method for manufacturing the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1995-11-02 EP disclosed
US-5395540-A METHOD OF HEAT TRANSFER HOECHST AKTIENGESELLSCHAFT (DE) 1995-03-07 US disclosed
US-5286759-A Preparing fine closed-cell foam by reacting polyisocyanate with reactive material in presence of water and blowing agent mixture of hydrocarbon and polyfluorocarbon THE DOW CHEMICAL COMPANY (US) 1994-02-15 US disclosed
EP-0575543-A1 FOAMING SYSTEM FOR RIGID URETHANE AND ISOCYANURATE FOAMS. DOW CHEMICAL CO (US) 1993-12-29 EP disclosed
WO-1993005200-A1 AZEOTROPE-LIKE COMPOSITIONS OF 1,1-DICHLORO-1-FLUOROETHANE AND PERFLUOROCARBONS AND OPTIONALLY NITROMETHANE ALLIED-SIGNAL INC. (US) 1993-03-18 WO disclosed
WO-1992015639-A1 FOAMING SYSTEM FOR RIGID URETHANE AND ISOCYANURATE FOAMS THE DOW CHEMICAL COMPANY (US) 1992-09-17 WO disclosed
US-3950235-A ELECTROLYTIC METHOD OF PRODUCING BRANCHED PERFLUORO-ALKANES HOECHST AKTIENGESELLSCHAFT (DT) 1976-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150065519-A1 HETEROCYCLIC COMPOUNDS AND METHODS OF USE HRAS, VHL, ESRRB LMNA 2671/4885
US-12540073-B2 Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor SCO2, SOD1, HAO2 LMNA 4529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.