Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.61 |
| ▸ | CTSK | P43235 | 2/20 | 0.61 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 3/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540730 | 1.00 | CTSS (0.61) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL7263678 | 0.91 | CTSS (0.55) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL4216537 | 0.88 | CTSS (0.56) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL4216541 | 0.88 | CTSS (0.56) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL4216552 | 0.88 | CTSS (0.56) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL31069953 | 0.88 | CTSS (0.62) | CTSSCTSKCTSLCTSBPSENEN | |
| SCHEMBL5663757 | 0.88 | CTSS (0.58) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL18766187 | 0.85 | CTSS (0.68) | CTSSCTSKPSENENCA2 | |
| SCHEMBL11405307 | 0.85 | CTSS (0.68) | CTSSCTSKPSENENCA2 | |
| SCHEMBL7787127 | 0.85 | CTSS (0.58) | CTSSCTSKPSENENCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993000359-A1 | MODIFIED PEPTIDES TRANSPORTABLE INTO THE CENTRAL NERVOUS SYSTEM | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-01-07 | — | — | WO | disclosed |