Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.55 |
| ▸ | CTSK | P43235 | 4/20 | 0.55 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540730 | 0.91 | CTSS (0.61) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL9540722 | 0.91 | CTSS (0.61) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL629960 | 0.89 | CTSS (0.67) | CTSSCTSKKMT2AALDH1A1 | |
| SCHEMBL627379 | 0.89 | CTSS (0.67) | CTSSCTSKKMT2AALDH1A1 | |
| SCHEMBL2159319 | 0.89 | CTSS (0.67) | CTSSCTSKKMT2AALDH1A1 | |
| SCHEMBL1951088 | 0.89 | CTSS (0.67) | CTSSCTSKKMT2AALDH1A1 | |
| SCHEMBL905289 | 0.89 | CTSS (0.67) | CTSSCTSKKMT2AALDH1A1 | |
| SCHEMBL3205842 | 0.89 | CTSS (0.67) | CTSSCTSKKMT2AALDH1A1 | |
| SCHEMBL3825684 | 0.89 | CTSS (0.67) | CTSSCTSKKMT2AALDH1A1 | |
| SCHEMBL16710011 | 0.89 | CTSS (0.67) | CTSSCTSKKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003101449-A2 | PROCESS FOR THE PREPARATION OF 3,3,4,4-TETRAFLUOROPYRROLIDINE AND DERIVATIVES THEREOF | PFIZER PRODUCTS INC. (US) | 2003-12-11 | — | — | WO | disclosed |